Synthesis of mycophenolic acid by palladium-catalyzed three component coupling reaction

I. Shimizu; Y. Lee; Y. Fujiwara

Synthesis of mycophenolic acid by palladium-catalyzed three component coupling reaction

I. Shimizu, Y. Lee, Y. Fujiwara

早稲田大学

研究成果: Article › 査読

12 被引用数 (Scopus)

抄録

Reaction of aromatic iodide 3 with isoprene and dimethyl malonate in the presence of palladium(0) catalyst gave the coupling product 4, which was converted into mycophenolic acid (1) in three steps.

本文言語	English
ページ（範囲）	1285-1286
ページ数	2
ジャーナル	Synlett
号	9
出版ステータス	Published - 2000

ASJC Scopus subject areas

有機化学

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引用スタイル

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title = "Synthesis of mycophenolic acid by palladium-catalyzed three component coupling reaction",

abstract = "Reaction of aromatic iodide 3 with isoprene and dimethyl malonate in the presence of palladium(0) catalyst gave the coupling product 4, which was converted into mycophenolic acid (1) in three steps.",

keywords = "π-allylpalladium intermediate, Mycophenolic acid, Palladium(0), Phthalide, Three component coupling reaction",

author = "I. Shimizu and Y. Lee and Y. Fujiwara",

year = "2000",

language = "English",

pages = "1285--1286",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

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T1 - Synthesis of mycophenolic acid by palladium-catalyzed three component coupling reaction

AU - Shimizu, I.

AU - Lee, Y.

AU - Fujiwara, Y.

PY - 2000

Y1 - 2000

N2 - Reaction of aromatic iodide 3 with isoprene and dimethyl malonate in the presence of palladium(0) catalyst gave the coupling product 4, which was converted into mycophenolic acid (1) in three steps.

AB - Reaction of aromatic iodide 3 with isoprene and dimethyl malonate in the presence of palladium(0) catalyst gave the coupling product 4, which was converted into mycophenolic acid (1) in three steps.

KW - π-allylpalladium intermediate

KW - Mycophenolic acid

KW - Palladium(0)

KW - Phthalide

KW - Three component coupling reaction

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JO - Synlett

JF - Synlett

SN - 0936-5214

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Synthesis of mycophenolic acid by palladium-catalyzed three component coupling reaction

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