@article{28ed05b4338b4e7e87bd04144cac76e7,
title = "Synthesis of Octaaryl Naphthalenes and Anthracenes with Different Substituents",
abstract = "A synthesis of multiply arylated naphthalenes and anthracenes with eight different substituents has been accomplished. The key intermediates are tetraarylthiophene S-oxides, which are synthesized through a method involving sequential C−H arylation and cross-coupling from 3-methoxythiophene, followed by oxidation of the sulfur atom. The resulting tetraarylthiophene S-oxides can be converted into a tetraaryl benzynes or naphthalynes and then merged through [4+2] cycloaddition reaction with another tetraarylthiophene S-oxide, thereby resulting in the programmed synthesis of octaarylnaphthalenes and octaarylanthracenes.",
keywords = "arenes, arynes, cycloaddition, molecular diversity, polycycles",
author = "Shin Suzuki and Kenichiro Itami and Junichiro Yamaguchi",
note = "Funding Information: This work was supported by JSPS KAKENHI Grant Number JP16H01011, JP16H01140, JP16H04148 (to J.Y.), the ERATO program from JST (to K.I.), and a JSPS research fellowship for young scientists (to S.S.). We also thanks Dr. Yasutomo Segawa and Kenta Kato for assistance with X-ray crystal structure analysis and computational studies. We thank Dr. Yoshihiro Ishihara (Vertex Pharmaceuticals) for fruitful discussion and critical comments. ITbM is supported by the World Premier International Research Center (WPI) Initiative, Japan. Publisher Copyright: {\textcopyright} 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2017",
month = nov,
day = "20",
doi = "10.1002/anie.201709332",
language = "English",
volume = "56",
pages = "15010--15013",
journal = "Angewandte Chemie - International Edition",
issn = "1433-7851",
publisher = "John Wiley and Sons Ltd",
number = "47",
}