Synthesis of polyunsaturated fatty acid-containing glucuronosyl-diacylglycerol through direct glycosylation

Qianqian Wang, Yuta Kuramoto, Yozo Okazaki, Eisuke Ota, Masaki Morita, Go Hirai*, Kazuki Saito, Mikiko Sodeoka

*この研究の対応する著者

研究成果査読

3 被引用数 (Scopus)

抄録

We describe a total synthesis of a polyunsaturated fatty acid (PUFA)-containing glucuronosyldiacylglycerol (GlcADG), which is a surrogate glycolipid whose synthesis is remarkably upregulated in plant membranes under phosphorus-depleted conditions. Glycosylation between the glucuronide donor bearing 3,4-dimethoxybenzyl (DMPM) protecting groups and di-acylglycerol acceptor proceeded smoothly in the presence of gold(I) catalyst to provide the protected α-isomer of GlcADG as the major product.

本文言語English
ページ(範囲)2915-2918
ページ数4
ジャーナルTetrahedron Letters
58
30
DOI
出版ステータスPublished - 2017
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

フィンガープリント

「Synthesis of polyunsaturated fatty acid-containing glucuronosyl-diacylglycerol through direct glycosylation」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル