Synthesis of porphinatoirons having an alkyl amphiphilic chain and their O2 binding properties in lipid bilayers

Eishun Tsuchida*, Hiroyuki Nishide, Etsuo Hasegawa, Yuzuru Chika, Masaki Fukuzumi, Teruyuki Komatsu

*この研究の対応する著者

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Synthesis and characterization of two amphiphilic tetraphenylporphinatoiron complexes having a glycerophosphocholine or an alkyl phosphoserine group are described. These porphinatoiron(II) complexes with 1-dodecyl-2-methyl-imidazole (L2MIm) were efficiently embedded in the bilayer of a phospholipid vesicle due to their high compatibility with lipids, similar to the heme substituted with four alkyl amphiphilic chains (lipid-heme). Oxygen transporting ability of the phospholipid vesicles embedded with hemes were similar to that of hemoglobin (Hb) in red blood cells.

本文言語English
ページ(範囲)255-264
ページ数10
ジャーナルJournal of Inorganic Biochemistry
49
4
DOI
出版ステータスPublished - 1993

ASJC Scopus subject areas

  • 生化学
  • 無機化学

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