Synthesis of the C1-C17 Segment of Bafilomycin N

Haruka Sato, Seijiro Hosokawa

研究成果: Article査読

1 被引用数 (Scopus)

抄録

The C1-C17 segment of bafilomycin N has been synthesized. The C1-C11 segment was synthesized by the anti -selective vinylogous Mukaiyama aldol reaction with a chiral vinylketene silyl N, O -acetal and the Horner-Wadsworth-Emmons reaction, whereas C12-C17 was constructed by the syn -selective vinylogous Mukaiyama aldol reaction and the Jung's semipinacol rearrangement. Those segments were connected by the Stille coupling to afford the C1-C17 segment.

本文言語English
ページ(範囲)577-580
ページ数4
ジャーナルSynlett
30
5
DOI
出版ステータスPublished - 2019

ASJC Scopus subject areas

  • Organic Chemistry

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