Synthesis of the C1-C17 Segment of Bafilomycin N

Haruka Sato, Seijiro Hosokawa

    研究成果: Article

    1 引用 (Scopus)

    抄録

    The C1-C17 segment of bafilomycin N has been synthesized. The C1-C11 segment was synthesized by the anti -selective vinylogous Mukaiyama aldol reaction with a chiral vinylketene silyl N, O -acetal and the Horner-Wadsworth-Emmons reaction, whereas C12-C17 was constructed by the syn -selective vinylogous Mukaiyama aldol reaction and the Jung's semipinacol rearrangement. Those segments were connected by the Stille coupling to afford the C1-C17 segment.

    元の言語English
    ページ（範囲）577-580
    ページ数4
    ジャーナルSynlett
    巻30
    発行部数5
    DOI
    出版物ステータスPublished - 2019 1 1

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    Acetals
    3-hydroxybutanal
    semipinacol

    ASJC Scopus subject areas

    • Organic Chemistry

    これを引用

    Synthesis of the C1-C17 Segment of Bafilomycin N. / Sato, Haruka; Hosokawa, Seijiro.

    ：: Synlett, 巻 30, 番号 5, 01.01.2019, p. 577-580.

    研究成果: Article

    Sato, H & Hosokawa, S 2019, 'Synthesis of the C1-C17 Segment of Bafilomycin N', Synlett, 巻. 30, 番号 5, pp. 577-580. https://doi.org/10.1055/s-0037-1611727
    Sato H, Hosokawa S. Synthesis of the C1-C17 Segment of Bafilomycin N. Synlett. 2019 1 1;30(5):577-580. https://doi.org/10.1055/s-0037-1611727
    Sato, Haruka ; Hosokawa, Seijiro. / Synthesis of the C1-C17 Segment of Bafilomycin N. ：: Synlett. 2019 ; 巻 30, 番号 5. pp. 577-580.
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    KW - vinylogous Mukaiyama aldol reaction

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