Synthetic studies on taxol: Highly stereoselective construction of the taxol C-ring via SN2′ reduction of an allylic phosphonium salt

Masayuki Utsugi, Masayuki Miyano, Masahisa Nakada*

*この研究の対応する著者

研究成果: Article査読

12 被引用数 (Scopus)

抄録

The highly stereoselective construction of the C3 stereogenic center of the taxol C-ring is described. The trans isomer at the C3-C8 position of the taxol C-ring, which is required for the total synthesis, as well as its diastereomeric cis isomer were successfully synthesized with highly diastereoselective S N2′ reduction of the allylic phosphonium salts.

本文言語English
ページ(範囲)2973-2976
ページ数4
ジャーナルOrganic Letters
8
14
DOI
出版ステータスPublished - 2006 7 6

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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