Tb 3+-enhanced potentiometric detection of single nucleotide polymorphism by field effect transistors

研究成果: Article査読

5 被引用数 (Scopus)

抄録

The use of Tb 3+ as a center ion and media to introduce more exogenously negative charges onto double-stranded DNA (dsDNA), can greatly enhance potentiometric signals produced by the shift of gate voltage of field effect transisitor (FET). Furthermore, different affinities of Tb 3+ to normal and mismatched dsDNAs amplified the signal difference between their detections, which can improve the discrimination of single nucleotide polymorphism.

本文言語English
ページ(範囲)376-377
ページ数2
ジャーナルChemistry Letters
38
4
DOI
出版ステータスPublished - 2009 7 20

ASJC Scopus subject areas

  • Chemistry(all)

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