Temperature-responsiveness and antimicrobial properties of CNT-PNIPAM hybrid brush films

Katrina D. Pangilinan, Catherine M. Santos, Nicel C. Estillore, Debora F. Rodrigues, Rigoberto C. Advincula*


研究成果: Article査読

19 被引用数 (Scopus)


Temperature-responsive carbon nanotube (CNT)/poly(N-isopropylacrylamide) (PNIPAM) hybrid brush films were prepared by combining the layer-by-layer and surface-initiated polymerization (LbL-SIP) techniques. Atom transfer radical polymerization (ATRP) is employed for the preparation of PNIPAM polymer brushes. Antibacterial activity of the CNT/PNIPAM films are investigated against Exiguobacterium sp. AT1b and Exiguobacterium sibiricum strains. Dead assay results show high microbial inactivation on coated surfaces with CNT films, while very low microbial inactivation is observed in PNIPAM films at all temperatures tested. The CNT-PNIPAM films, on the other hand, have antibacterial properties below 32 °C, which is below the lower critical solution temperature (LCST), but allows biofilm formation above the LCST. Carbon nanotubes incorporated via layer-by-layer assembly in ultra-thin films with temperature-sensitive polymer brushes exhibit unique antibacterial properties tunable with temperature. These hybrid films are useful for actively preventing biofilm formation at various temperature conditions and can be employed as smart coatings.

ジャーナルMacromolecular Chemistry and Physics
出版ステータスPublished - 2013 2月 25

ASJC Scopus subject areas

  • 凝縮系物理学
  • 物理化学および理論化学
  • ポリマーおよびプラスチック
  • 有機化学
  • 材料化学


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