The caudal periaqueductal gray participates in the activation of brown adipose tissue in rats

Xiao Ming Chen, Maiko Nishi, Aki Taniguchi, Kei Nagashima, Masaaki Shibata, Kazuyuki Kanosue*

*この研究の対応する著者

研究成果査読

34 被引用数 (Scopus)

抄録

To investigate the involvement of the periaqueductal gray (PAG) in the control of non-shivering thermogenesis, we tested the effects of electrical or chemical stimulation of the PAG on thermogenesis of brown adipose tissue (BAT) in urethane anesthetized rats. Electrical stimulation (0.1 mA, 33 Hz, 0.5 ms) or application of D,L-homocysteic acid (0.5 mM, 0.3 μl) into the lateral region of the caudal PAG (cPAG) elicited BAT thermogenesis, measured as a rise in the local temperature of interscapular BAT. These results suggest that neurons in the cPAG send excitatory efferent signals for BAT thermogenesis.

本文言語English
ページ(範囲)17-20
ページ数4
ジャーナルNeuroscience Letters
331
1
DOI
出版ステータスPublished - 2002 10 4
外部発表はい

ASJC Scopus subject areas

  • 神経科学(全般)

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