The caudal periaqueductal gray participates in the activation of brown adipose tissue in rats

Xiao Ming Chen, Maiko Nishi, Aki Taniguchi, Kei Nagashima, Masaaki Shibata, Kazuyuki Kanosue

研究成果: Article

33 引用 (Scopus)

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To investigate the involvement of the periaqueductal gray (PAG) in the control of non-shivering thermogenesis, we tested the effects of electrical or chemical stimulation of the PAG on thermogenesis of brown adipose tissue (BAT) in urethane anesthetized rats. Electrical stimulation (0.1 mA, 33 Hz, 0.5 ms) or application of D,L-homocysteic acid (0.5 mM, 0.3 μl) into the lateral region of the caudal PAG (cPAG) elicited BAT thermogenesis, measured as a rise in the local temperature of interscapular BAT. These results suggest that neurons in the cPAG send excitatory efferent signals for BAT thermogenesis.

元の言語English
ページ(範囲)17-20
ページ数4
ジャーナルNeuroscience Letters
331
発行部数1
DOI
出版物ステータスPublished - 2002 10 4
外部発表Yes

ASJC Scopus subject areas

  • Neuroscience(all)

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