The development and evaluation of a prototype system for the inference of genetic networks based on genetic programming

Kouji Tanaka*, Hayato Yamana

*この研究の対応する著者

研究成果: Conference contribution

抄録

Estimating mutual interactions of genetic networks is mainly to infer the mutual control relationships from multiple genes from the gene expression data. Such correlations are typically expressible in the form of nonlinear simultaneous differential equations. However, most work to date has employed S-systems as an expression of such differential equations, allowing only rough approximations of mass actions, and as such it was difficult to determine the actual correlations between the genes. Instead, we formulate the mutual interactions as actual simultaneous partial differential equations, and automatically determine its structure and coefficients using genetic programming (GP) from a given data series. Parallel implementation of the scheme in a Grid environment using our Jojo Grid programming system for Java has resulted in precise determination of the equations in many cases within some reasonable time.

本文言語English
ホスト出版物のタイトルWMSCI 2007 - The 11th World Multi-Conference on Systemics, Cybernetics and Informatics, Jointly with the 13th International Conference on Information Systems Analysis and Synthesis, ISAS 2007 - Proc.
ページ13-18
ページ数6
出版ステータスPublished - 2007 12 1
イベント11th World Multi-Conference on Systemics, Cybernetics and Informatics, WMSCI 2007, Jointly with the 13th International Conference on Information Systems Analysis and Synthesis, ISAS 2007 - Orlando, FL, United States
継続期間: 2007 7 82007 7 11

出版物シリーズ

名前WMSCI 2007 - The 11th World Multi-Conference on Systemics, Cybernetics and Informatics, Jointly with the 13th International Conference on Information Systems Analysis and Synthesis, ISAS 2007 - Proc.
4

Conference

Conference11th World Multi-Conference on Systemics, Cybernetics and Informatics, WMSCI 2007, Jointly with the 13th International Conference on Information Systems Analysis and Synthesis, ISAS 2007
国/地域United States
CityOrlando, FL
Period07/7/807/7/11

ASJC Scopus subject areas

  • 人工知能
  • 情報システム

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