This study aimed to investigate the effect of active workstation designs on sitting, standing and walking during simple typing and pad pointing, and combined tasks for office job. The gradual shift from manufacturing to service industries, combined with technological advanced has resulted in increasing number of people employed in sedentary occupations. It was well known that prolonged sitting was to associate with an increased risk of premature mortality and high levels of sitting cannot be compensated for leisure-time physical activity. Sedentary behavior as sitting computer operation should not be viewed as simply the absence of physical activity or as the extreme lower muscles of lacing physical activity. 13 females performed 20-min office work as typing and searching tasks in each posture, siting, standing desk and standing desk with walking while Oxygen uptake data and HR values was recorded. On the first occasion, a brief description of the test procedures and apparat us was repeated both orally and in writing. They performed on a treadmill to determine their individual oxygen uptake (VO2) and office work like several tasks. Mainly finding showed that walking had significantly higher VO2 than sitting and standing. Moreover, studies have found no effect of Changes in working posture like sitting and standing on computer work performance. Insufficient physical activity is a major threat to health and productivity of office workers. The study confirmed that the difference in energy expenditure of tasks carried out in sitting compared to standing is negligible. Therefore, it is considered that providing exercise habits such as standing and walking while performing office work is an opportunity to eliminate lack of exercise by employees. Rather than sitting all the time, sometimes changing postures and working was considered as one of the health management of employees.