The effects of beta-hydroxy-beta-methylbutyrate-free acidsupplementation and resistance training on oxidative stress markers: A randomized,double-blind, placebo-controlled study

Hamid Arazi*, Abbas Asadi, Katsuhiko Suzuki

*この研究の対応する著者

研究成果: Article査読

5 被引用数 (Scopus)

抄録

The aim of this study was to investigate the effects of 6-week beta-hydroxy-beta methylbutyrate-free acid (HMB-FA) supplementation on oxidative stress and biochemical variablesin responses to resistance training. Sixteen healthy young males participated in this study and were randomly assigned to a HMB-FA supplementation group (n = 8) or a placebo supplementation group (n = 8). The resistance training program was applied for 6 weeks with two sessions per week. Blood samples were collected before and after training, and 8-hydroxy-2-deoxyguanosine (8-OHdG), malondialdehyde (MDA), protein carbonyl (PC), and biochemical variables, such as alanine transaminase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and the numbers of total white blood cells (WBC), neutrophils, lymphocytes, and monocytes were analyzed.Following intervention, both the HMB-FA and placebo supplementation groups showed significant decreases in MDA (effect size [ES]; 0.39, 0.33) and PC (ES; 1.37,1.41), respectively. However,8-OHdG did not change after 6 weeks of training in any of the groups. In addition, both groups showed similar training effects on biochemical variables after 6 weeks of intervention. It was concluded that HMB-FA supplementation during resistance training did not add further adaptive changes related to oxidative stress markers.

本文言語English
論文番号76
ジャーナルAntioxidants
7
6
DOI
出版ステータスPublished - 2018 6 11

ASJC Scopus subject areas

  • 生化学
  • 生理学
  • 分子生物学
  • 臨床生化学
  • 細胞生物学

フィンガープリント

「The effects of beta-hydroxy-beta-methylbutyrate-free acidsupplementation and resistance training on oxidative stress markers: A randomized,double-blind, placebo-controlled study」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル