抄録
The first total synthesis and structural determination of (+)-BE-52440A have been achieved by enantiodivergent synthesis. S-Bridging dimerization including SN2 epoxy-opening reaction of tetrasubstituted epoxide 2 with sodium sulfide has been achieved in excellent yield with high regioselectivity. The structure of (+)-BE-52440A was determined to be the dimer of kalafungin type pyranonaphthoquinone.
本文言語 | English |
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ページ(範囲) | 8018-8021 |
ページ数 | 4 |
ジャーナル | Tetrahedron Letters |
巻 | 48 |
号 | 45 |
DOI | |
出版ステータス | Published - 2007 11 5 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry