The first total synthesis and structural determination of TMC-264

Kuniaki Tatsuta, Akiho Furuyama, Tomoe Yano, Yasuaki Suzuki, Takashi Ogura, Seijiro Hosokawa

    研究成果: Article

    8 引用 (Scopus)

    抄録

    The first total synthesis and structural determination of TMC-264 has been accomplished. Regioselective bromination, regioselective methoxymethylation, and nickel(0)-Lewis acid-mediated cyclization afforded multi-functionalized 1-methyl-dibenzo[b,d]-pyran skeleton.

    元の言語English
    ページ(範囲)4036-4039
    ページ数4
    ジャーナルTetrahedron Letters
    49
    発行部数25
    DOI
    出版物ステータスPublished - 2008 6 16

    Fingerprint

    Pyrans
    Lewis Acids
    Halogenation
    Cyclization
    Nickel
    Skeleton
    TMC-264

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    これを引用

    The first total synthesis and structural determination of TMC-264. / Tatsuta, Kuniaki; Furuyama, Akiho; Yano, Tomoe; Suzuki, Yasuaki; Ogura, Takashi; Hosokawa, Seijiro.

    :: Tetrahedron Letters, 巻 49, 番号 25, 16.06.2008, p. 4036-4039.

    研究成果: Article

    Tatsuta, K, Furuyama, A, Yano, T, Suzuki, Y, Ogura, T & Hosokawa, S 2008, 'The first total synthesis and structural determination of TMC-264', Tetrahedron Letters, 巻. 49, 番号 25, pp. 4036-4039. https://doi.org/10.1016/j.tetlet.2008.04.074
    Tatsuta, Kuniaki ; Furuyama, Akiho ; Yano, Tomoe ; Suzuki, Yasuaki ; Ogura, Takashi ; Hosokawa, Seijiro. / The first total synthesis and structural determination of TMC-264. :: Tetrahedron Letters. 2008 ; 巻 49, 番号 25. pp. 4036-4039.
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    AU - Hosokawa, Seijiro

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