The first total synthesis and structural determination of TMC-66

Seijiro Hosokawa, Hitoshi Fumiyama, Hisato Fukuda, Tomohiro Fukuda, Masashi Seki, Kuniaki Tatsuta

研究成果: Article

21 引用 (Scopus)

抜粋

The first total synthesis and structural determination of TMC-66, an ECE inhibitor, was achieved in short steps by efficient construction and coupling of segments. The oxidative coupling with phenols attaching to electron-withdrawing groups was realized with a novel copper(II) reagent.

元の言語English
ページ(範囲)7305-7308
ページ数4
ジャーナルTetrahedron Letters
48
発行部数41
DOI
出版物ステータスPublished - 2007 10 8

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

フィンガープリント The first total synthesis and structural determination of TMC-66' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Hosokawa, S., Fumiyama, H., Fukuda, H., Fukuda, T., Seki, M., & Tatsuta, K. (2007). The first total synthesis and structural determination of TMC-66. Tetrahedron Letters, 48(41), 7305-7308. https://doi.org/10.1016/j.tetlet.2007.08.037