抄録
The first total synthesis and structural determination of TMC-66, an ECE inhibitor, was achieved in short steps by efficient construction and coupling of segments. The oxidative coupling with phenols attaching to electron-withdrawing groups was realized with a novel copper(II) reagent.
本文言語 | English |
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ページ(範囲) | 7305-7308 |
ページ数 | 4 |
ジャーナル | Tetrahedron Letters |
巻 | 48 |
号 | 41 |
DOI | |
出版ステータス | Published - 2007 10 8 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry