The first total synthesis and structural determination of TMC-66

Seijiro Hosokawa, Hitoshi Fumiyama, Hisato Fukuda, Tomohiro Fukuda, Masashi Seki, Kuniaki Tatsuta

研究成果: Article査読

21 被引用数 (Scopus)

抄録

The first total synthesis and structural determination of TMC-66, an ECE inhibitor, was achieved in short steps by efficient construction and coupling of segments. The oxidative coupling with phenols attaching to electron-withdrawing groups was realized with a novel copper(II) reagent.

本文言語English
ページ(範囲)7305-7308
ページ数4
ジャーナルTetrahedron Letters
48
41
DOI
出版ステータスPublished - 2007 10 8

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

フィンガープリント 「The first total synthesis and structural determination of TMC-66」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル