抄録
The first total synthesis and structural determination of YCM1008A, a Ca2+ signaling inhibitor, have been achieved. The N-methoxy pyrano-pyridone moiety was synthesized by successive O- and N-conjugate additions with diketoamide 15. The absolute structure was determined to be (2R,3R,4S,8′R)-configuration.
本文言語 | English |
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ページ(範囲) | 4187-4190 |
ページ数 | 4 |
ジャーナル | Tetrahedron Letters |
巻 | 48 |
号 | 24 |
DOI | |
出版ステータス | Published - 2007 6 11 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry