The first total synthesis and structural determination of YCM1008A

Kuniaki Tatsuta, Takahiro Yamaguchi, Yusuke Tsuda, Yumiko Yamaguchi, Nobutaka Hattori, Hiroshi Nagai, Seijiro Hosokawa

    研究成果: Article

    16 引用 (Scopus)

    抄録

    The first total synthesis and structural determination of YCM1008A, a Ca2+ signaling inhibitor, have been achieved. The N-methoxy pyrano-pyridone moiety was synthesized by successive O- and N-conjugate additions with diketoamide 15. The absolute structure was determined to be (2R,3R,4S,8′R)-configuration.

    元の言語English
    ページ（範囲）4187-4190
    ページ数4
    ジャーナルTetrahedron Letters
    巻48
    発行部数24
    DOI
    出版物ステータスPublished - 2007 6 11

    Fingerprint

    Pyridones
    YCM 1008A

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    これを引用

    Tatsuta, K., Yamaguchi, T., Tsuda, Y., Yamaguchi, Y., Hattori, N., Nagai, H., & Hosokawa, S. (2007). The first total synthesis and structural determination of YCM1008A. Tetrahedron Letters, 48(24), 4187-4190. https://doi.org/10.1016/j.tetlet.2007.04.074

    The first total synthesis and structural determination of YCM1008A. / Tatsuta, Kuniaki; Yamaguchi, Takahiro; Tsuda, Yusuke; Yamaguchi, Yumiko; Hattori, Nobutaka; Nagai, Hiroshi; Hosokawa, Seijiro.

    ：: Tetrahedron Letters, 巻 48, 番号 24, 11.06.2007, p. 4187-4190.

    研究成果: Article

    Tatsuta, K, Yamaguchi, T, Tsuda, Y, Yamaguchi, Y, Hattori, N, Nagai, H & Hosokawa, S 2007, 'The first total synthesis and structural determination of YCM1008A', Tetrahedron Letters, 巻. 48, 番号 24, pp. 4187-4190. https://doi.org/10.1016/j.tetlet.2007.04.074
    Tatsuta K, Yamaguchi T, Tsuda Y, Yamaguchi Y, Hattori N, Nagai H その他. The first total synthesis and structural determination of YCM1008A. Tetrahedron Letters. 2007 6 11;48(24):4187-4190. https://doi.org/10.1016/j.tetlet.2007.04.074
    Tatsuta, Kuniaki ; Yamaguchi, Takahiro ; Tsuda, Yusuke ; Yamaguchi, Yumiko ; Hattori, Nobutaka ; Nagai, Hiroshi ; Hosokawa, Seijiro. / The first total synthesis and structural determination of YCM1008A. ：: Tetrahedron Letters. 2007 ; 巻 48, 番号 24. pp. 4187-4190.
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    AU - Tsuda, Yusuke

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    AU - Hattori, Nobutaka

    AU - Nagai, Hiroshi

    AU - Hosokawa, Seijiro

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