The first total synthesis and structural determination of YCM1008A

Kuniaki Tatsuta; Takahiro Yamaguchi; Yusuke Tsuda; Yumiko Yamaguchi; Nobutaka Hattori; Hiroshi Nagai; Seijiro Hosokawa

doi:10.1016/j.tetlet.2007.04.074

The first total synthesis and structural determination of YCM1008A

Kuniaki Tatsuta, Takahiro Yamaguchi, Yusuke Tsuda, Yumiko Yamaguchi, Nobutaka Hattori, Hiroshi Nagai, Seijiro Hosokawa

先進理工学部

研究成果: Article

16 引用（Scopus）

抜粋

The first total synthesis and structural determination of YCM1008A, a Ca²⁺ signaling inhibitor, have been achieved. The N-methoxy pyrano-pyridone moiety was synthesized by successive O- and N-conjugate additions with diketoamide 15. The absolute structure was determined to be (2R,3R,4S,8′R)-configuration.

元の言語	English
ページ（範囲）	4187-4190
ページ数	4
ジャーナル	Tetrahedron Letters
巻	48
発行部数	24
DOI	https://doi.org/10.1016/j.tetlet.2007.04.074
出版物ステータス	Published - 2007 6 11

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

文献にアクセス

10.1016/j.tetlet.2007.04.074

フィンガープリント The first total synthesis and structural determination of YCM1008A' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

これを引用

Tatsuta, K., Yamaguchi, T., Tsuda, Y., Yamaguchi, Y., Hattori, N., Nagai, H., & Hosokawa, S. (2007). The first total synthesis and structural determination of YCM1008A. Tetrahedron Letters, 48(24), 4187-4190. https://doi.org/10.1016/j.tetlet.2007.04.074

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AU - Tsuda, Yusuke

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AU - Hattori, Nobutaka

AU - Nagai, Hiroshi

AU - Hosokawa, Seijiro

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