Three-dimensional analysis of small airway with X-ray micro-CT

Toshihiro Sera, Yuji Hasegawa, Robert C. Schroter, Kazuo Tanishita

研究成果: Conference contribution

抄録

To identify the anatomy of small airways, we visualized and quantified the excised rat lung at varying lung volume using the microfocus X-ray CT. We insufflated tantalum dust as contrast agent. Lung volume was varied in steps from functional residual capacity (FRC: 2 mL) to the maximal lung capacity (MLC: 12 mL). At FRC we found out airway closure in small airways (Maximum lumen area was 0.06 mm 2 at MLC), where the bronchial walls are held in apposition. Lumen area dramatically varied at the first step during inflation and deflation, and the maximum area at MLC was 8 times as large as the minimum area at FRV.

本文言語English
ホスト出版物のタイトルAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
編集者R.D. Kamm, G.W. Schmid-Schoenbein, G.A. Atesian, M.S. Hefzy
ページ461-462
ページ数2
50
出版ステータスPublished - 2001
外部発表はい
イベントProceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States
継続期間: 2001 6 272001 7 1

Other

OtherProceedings of the 2001 Bioengineering Conference
国/地域United States
CitySnowbird, UT
Period01/6/2701/7/1

ASJC Scopus subject areas

  • 工学(全般)

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