Three-dimensional pathological analysis of cerebral aneurysm initiation

Xinning Wang*, Kenta Suto, Takanobu Yagi, Koichi Kawamura, Mitsuo Umezu

*この研究の対応する著者

研究成果: Conference contribution

抄録

Cerebral aneurysm is known to initiate at the cerebral artery bifurcation. The pathological mechanism of cerebral aneurysm awaits further understanding especially on its initiation. This study sought to elucidate the three-dimensional structure of cerebral vascular bifurcations with and without aneurysms using human cadavers. The two cases had aneurysmal initiations out of total 7 cases. The studied structure was intimal hyperplasia, tunica media and internal elastic lamina, which were recognized by elastica masson staining. The results showed that the non-existence of tunica media and internal elastic lamina was found in the lesion without aneurysm. The non-existence of intimal hyperplasia was only found in the lesion with aneurysm. These data suggest that the formation of intimal hyperplasia may be related with the initiation of aneurysm. We regarded the boundary of existence arteriosclerosis as the position for new arteriosclerosis occurs and thought the direction of new arteriosclerosis grows would influence whether the cerebral aneurysm initiates or not.

本文言語English
ホスト出版物のタイトルAdvanced Computational Methods in Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2017 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017, Proceedings
編集者Minrui Fei, Shiwei Ma, Xin Li, Xin Sun, Li Jia, Zhou Su
出版社Springer Verlag
ページ95-103
ページ数9
ISBN(印刷版)9789811063695
DOI
出版ステータスPublished - 2017
イベントInternational Conference on Life System Modeling and Simulation, LSMS 2017 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017 - Nanjing, China
継続期間: 2017 9月 222017 9月 24

出版物シリーズ

名前Communications in Computer and Information Science
761
ISSN(印刷版)1865-0929

Other

OtherInternational Conference on Life System Modeling and Simulation, LSMS 2017 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017
国/地域China
CityNanjing
Period17/9/2217/9/24

ASJC Scopus subject areas

  • コンピュータ サイエンス(全般)
  • 数学 (全般)

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