Time-dependent effect of glutamate on long-term potentiation in the suprachiasmatic nucleus of rats

Yukiko Nisikawa, Takao Shimazoe*, Shigenobu Shibata, Shigenori Watanabe

*この研究の対応する著者

研究成果: Article査読

10 被引用数 (Scopus)

抄録

The effect of glutamate on optic nerve stimulation-evoked field potentials in rat suprachiasmatic nucleus (SCN) was examined in vitro. Glutamate application for 20 min induced long-term potentiation (LTP) of the field potentials in the SCN at nighttime, whereas that induced a weak LTP at daytime. On the other hand, application for 40 min induced LTP in the SCN during the daytime, whereas it induced a weak one at nighttime. These results indicate that the effect of glutamate is dependent on the application time and that the effect is influenced by the duration of glutamate exposure.

本文言語English
ページ(範囲)201-204
ページ数4
ジャーナルJapanese Journal of Pharmacology
90
2
DOI
出版ステータスPublished - 2002 10 1
外部発表はい

ASJC Scopus subject areas

  • 薬理学

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