A highly stereoselective HfCl4-mediated Diels-Alder reaction of furan and the chiral acrylate ester of Corey's auxiliary to subsequently give 1, and the realization of the postulated biosynthetic pathway for the construction of epoxyquinols A and B, namely, oxidative 6π electrocyclization, followed by Diels-Alder reaction of the unprotected monomer are the key steps in the asymmetric total synthesis of (+)-epoxyquinols A and B.
|ジャーナル||Angewandte Chemie - International Edition|
|出版ステータス||Published - 2002 9月 2|
ASJC Scopus subject areas
- 化学 (全般)