Research and developments in Semantic Grid computing has gained much attention in areas of knowledge discovery, medical sciences, business world, among others. Dealing with large domain ontology in this computing environment and its complexity becomes a daunting task. The idea of ontology tailoring is to cope up and minimize the complexity in dealing with large domain ontology and to provide services for ontology reuse, extension, addition, merging, and replace. In this paper, we tackle the task in developing the models to provide the above-mentioned services and the framework for workflow composition in ontology tailoring using UML-based design. Workflow validations were conducted to verify towards realizing a workable ontology tailoring schemes.