Transfection microarrays for high-throughput phenotypic screening of genes involved in cell migration.

Reiko Onuki-Nagasaki*, Akira Nagasaki, Kazumi Hakamada, Taro Q.P. Uyeda, Satoshi Fujita, Masato Miyake, Jun Miyake

*この研究の対応する著者

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Cell migration is important in several biological phenomena, such as cancer metastasis. Therefore, the identification of genes involved in cell migration might facilitate the discovery of antimetastatic drugs. However, screening of genes by the current methods can be complicated by factors related to cell stimulation, for example, abolition of contact inhibition and the release inflammatory cytokines from wounded cells during examinations of wound healing in vitro. To overcome these problems and identify genes involved in cell migration, in this chapter we describe the use of transfection microarrays for high-throughput phenotypic screening.

本文言語English
ページ(範囲)193-203
ページ数11
ジャーナルMethods in molecular biology (Clifton, N.J.)
629
DOI
出版ステータスPublished - 2010
外部発表はい

ASJC Scopus subject areas

  • 分子生物学
  • 遺伝学

フィンガープリント

「Transfection microarrays for high-throughput phenotypic screening of genes involved in cell migration.」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル