tRNA recognition by CCA-adding enzyme.

Yukihide Tomari, Tsutomu Suzuki, Takuya Ueda

研究成果: Article

4 引用 (Scopus)

抄録

The CCA-adding enzyme [ATP (CTP): tRNA nucleotidyltransferase (EC. 2.7.7.25)] catalyzes the addition of the conserved CCA sequence to the 3'-terminus of tRNAs. It is known that CCA-adding enzymes from all three kingdoms recognize the elbow region of L-shape tRNA formed by the tertiary interaction between T-loop and D-loop. We here demonstrate that C. elegans mitochondrial CCA-adding enzyme has broad substrate specificity toward nematode mitochondrial tRNAs which lack entire T- or D-arms, by cloning and characterizing the recombinant protein.

元の言語English
ページ(範囲)77-78
ページ数2
ジャーナルNucleic acids research. Supplement (2001)
発行部数2
出版物ステータスPublished - 2002 1 1
外部発表Yes

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Transfer RNA
Conserved Sequence
Elbow
Substrate Specificity
Recombinant Proteins
Organism Cloning
Arm
tRNA nucleotidyltransferase

ASJC Scopus subject areas

  • Medicine(all)

これを引用

tRNA recognition by CCA-adding enzyme. / Tomari, Yukihide; Suzuki, Tsutomu; Ueda, Takuya.

:: Nucleic acids research. Supplement (2001), 番号 2, 01.01.2002, p. 77-78.

研究成果: Article

Tomari, Yukihide ; Suzuki, Tsutomu ; Ueda, Takuya. / tRNA recognition by CCA-adding enzyme. :: Nucleic acids research. Supplement (2001). 2002 ; 番号 2. pp. 77-78.
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