抄録
The CCA-adding enzyme [ATP (CTP): tRNA nucleotidyltransferase (EC. 2.7.7.25)] catalyzes the addition of the conserved CCA sequence to the 3'-terminus of tRNAs. It is known that CCA-adding enzymes from all three kingdoms recognize the elbow region of L-shape tRNA formed by the tertiary interaction between T-loop and D-loop. We here demonstrate that C. elegans mitochondrial CCA-adding enzyme has broad substrate specificity toward nematode mitochondrial tRNAs which lack entire T- or D-arms, by cloning and characterizing the recombinant protein.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 77-78 |
| ページ数 | 2 |
| ジャーナル | Nucleic acids research. Supplement (2001) |
| 号 | 2 |
| DOI | |
| 出版ステータス | Published - 2002 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 医学（全般）