Twelve-week jogging training increases pre-heparin serum lipoprotein lipase concentrations in overweight/obese middle-aged men

Masashi Miyashita, Miki Eto, Hiroyuki Sasai, Takehiko Tsujimoto, Yasuhiro Nomata, Kiyoji Tanaka

研究成果: Article査読

19 被引用数 (Scopus)

抄録

Aim: Enhancement of lipoprotein lipase (LPL) activity through drug administration has been shown to increase pre-heparin serum LPL concentrations; however, pre-heparin serum LPL responses to exercise training have not been determined. The present study was undertaken to investigate the effects of 12 weeks of supervised aerobic exercise training on pre-heparin serum LPL concentrations in overweight/obese men. Methods: Fifteen overweight/obese middle-aged men were assigned to one of two 12-week supervised exercise interventions: a walking group (eight participants gradually increasing brisk walking to 60 min/day 3 days a week) or a jogging group (seven participants gradually increasing jogging to 60 min/day 3 days a week). All participants maintained ad libitum diets. Blood samples were collected at baseline and immediately after 12 weeks. The primary outcome was pre-heparin serum LPL. Results: Pre-heparin serum LPL concentrations were increased in the jogging group after 12 weeks compared with the baseline values (mean±SEM: 37.6±4.7 vs. 51.0±6.6 ng/mL, respectively, p=0.033). In the walking group, pre-heparin serum LPL concentrations remained unchanged after 12 weeks. Conclusions: This study demonstrates that 12 weeks of jogging training increases pre-heparin serum LPL concentrations in overweight/obese middle-aged men.

本文言語English
ページ(範囲)21-29
ページ数9
ジャーナルJournal of Atherosclerosis and Thrombosis
17
1
DOI
出版ステータスPublished - 2010
外部発表はい

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine
  • Biochemistry, medical

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