Synthesis of a polymer nanosheet comprising the biocompatible and biodegradable polysaccharide-electrolytes and its ubiquitous transference from the silicone rubber substrate onto a human skin surface by fabricating a nano-adhesive plaster has been demonstrated. Chitosan and sodium alginate, which have amino and carboxylic groups as cationic and anionic polyelectrolytes at ambient pH were used to fabricate the polysaccharide nanosheet. A polyvinyl alcohol (PVA)membrane was prepared and used as a hydrophilic sacrificial membrane to transfer the polysaccharide nanosheet from the substrate onto the human skin. It was observed that the polymer nanosheet was no longer visible on the skin, as the surface relief of the skin perfectly matched that of the flexible sheet at the nanometer scale. The invisible nanosheet on the skin will have clear applications in the field of skin care.
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