Ultra-processed food consumption and adult diabetes risk: A systematic review and dose-response meta-analysis

Sajjad Moradi, Mohammad Ali Hojjati Kermani, Reza Bagheri, Hamed Mohammadi, Ahmad Jayedi, Melissa M. Lane, Omid Asbaghi, Sanaz Mehrabani*, Katsuhiko Suzuki

*この研究の対応する著者

研究成果: Review article査読

2 被引用数 (Scopus)

抄録

(1) Background: Recent individual studies have demonstrated that consumption of ultra-processed food (UPF) may be related to type two diabetes mellitus (T2DM). We aimed to synthe-size the results from these individual studies by conducting an updated systematic review and meta-analysis of observational studies evaluating the association between UPF consumption and the risk of T2DM. (2) Methods: A systematic search was conducted using ISI Web of Science, PubMed/MEDLINE and Scopus electronic databases from inception up to August 2021. Data were extracted from five studies (one cross-sectional study and four cohort studies, totaling 230,526 adults from four different countries). Risk ratios (RR) of pooled results were estimated using a random-effects model. (3) Results: Our results revealed that higher UPF consumption was significantly associated with an increased risk of T2DM (RR = 1.74; 95% CI: 1.36, 2.22; I2 = 68.9%; p < 0.001; n = 5). Linear dose-response analysis indicated that each 10% increase in UPF consumption (kcal/d) was associated with a 15% higher risk of T2DM (RR = 1.15; 95% CI: 1.06, 1.26; I2 = 86.0%; p < 0.001; n = 5) among adults. Non-linear dose-response analysis demonstrated a positive linear association between UPF consumption and T2DM (pnonlinearity = 0.13, pdose-response < 0.001; n = 5) among adults. (4) Conclusions: A higher intake of UPF was significantly associated with an increased risk of T2DM. However, underlying mechanisms remain unknown and future experimental studies are warranted.

本文言語English
論文番号4410
ジャーナルNutrients
13
12
DOI
出版ステータスPublished - 2021 12月

ASJC Scopus subject areas

  • 食品科学
  • 栄養および糖尿病

フィンガープリント

「Ultra-processed food consumption and adult diabetes risk: A systematic review and dose-response meta-analysis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル