Utilization of myosin and actin bundles for the transport of molecular cargo

Hideyo Takatsuki*, Kevin M. Rice, Shinichi Asano, B. Scott Day, Mizuki Hino, Kazuhiro Oiwa, Ryoki Ishikawa, Yuichi Hiratsuka, Taro Q.P. Uyeda, Kazuhiro Kohama, Eric R. Blough

*この研究の対応する著者

研究成果: Article査読

27 被引用数 (Scopus)

抄録

The utilization of motor proteins for the movement and assembly of synthetic components is currently a goal of nanoengineering research. Application of the myosin actin motor system for nanotechnological uses has been hampered due to the low flexural rigidity of individual F-actin filaments. Here it is demonstrated how actin bundling can be used to affect the translational behavior of myosin-propelled filaments, transport molecules across a motor-patterned surface, and that the movement of bundled actin can be regulated photonically. These data suggest that actin bundling may significantly improve the applicability of the myosin motor for future nanotechnological applications.

本文言語English
ページ(範囲)452-457
ページ数6
ジャーナルSmall
6
3
DOI
出版ステータスPublished - 2010 2 5
外部発表はい

ASJC Scopus subject areas

  • バイオテクノロジー
  • 生体材料
  • 化学 (全般)
  • 材料科学(全般)

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