Vascular aging and sarcopenia: Interactions with physiological functions during exercise

Naoyuki Hayashi*

*この研究の対応する著者

研究成果: Chapter

1 被引用数 (Scopus)

抄録

Sarcopenia includes reductions in the skeletal muscle mass, which could be related to the circulatory responses to exercise that support the degree of exertion associated with movements, the blood flow supporting the activities of neurons in the central and peripheral nervous systems, and the regulation of temperature, as well as supporting digestion and absorption. Reduced blood flow could be related to the pathological pathways of sarcopenia. Studies have shown that the age-related decline in blood flow reduces the exchange of oxygen, energy sources, metabolites, and heat between blood and cells, thereby aggravating the trophic state in cells. This chapter addresses vascular aging, focusing on the roles of the functions of skeletal muscle and cerebral, ocular, splanchnic, and skin vessels on locomotion and exercise. Sarcopenia could be bidirectionally related to marked impairments in the cardiovascular system resulting from reduced muscle activity.

本文言語English
ホスト出版物のタイトルSarcopenia
ホスト出版物のサブタイトルMolecular Mechanism and Treatment Strategies
出版社Elsevier
ページ249-265
ページ数17
ISBN(電子版)9780128221464
ISBN(印刷版)9780128226575
DOI
出版ステータスPublished - 2021 1月 1

ASJC Scopus subject areas

  • 医学(全般)

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