Versatile APD-based PET modules for high resolution, fast medical imaging

J. Kataoka*, H. Matsuda, M. Yoshino, T. Miura, F. Nishikido, M. Koizumi, T. Tanaka, H. Ikeda, Y. Ishikawa, N. Kawabata, Y. Matsunaga, S. Kishimoto, H. Kubo

*この研究の対応する著者

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

We report on the development of versatile APD-based PET modules with time-of-flight capability. The module consists of a LYSO matrix optically coupled with a position-sensitive avalanche photodiode (APD) array, and front-end circuits (FEC) directly connected to the rear-end of the APD package. Each APD device has a monolithic 16x16 (or 8x8) pixel structure with an active area of 1.0 (or 4.0) mm2 for each pixel. Time resolutions of 155 ps and 214 ps (FWHM) were obtained for 1.0 mm2 and 4.0 mm2 APD pixels, respectively, measured by the direct detection of 10 keV X-rays. The FEC carries two identical analog ASICs specifically designed for the APDs in TSMC 0.35 μm CMOS technology. Each ASIC consists of 32-channel charge-sensitive amplifiers, band-pass filters, differentiators, pulse-height and timing discriminators, and two-channel time-to-amplitude converters. The noise characteristic of the ASIC, mounted in a low temperature co-fired ceramics (LTCC) package, is 560 +30 e-/pF with an electric timing resolution of 484 ps (rms). The overall dimension of the module (including APD-array, LYSO matrix and FEC) is 30x30x80 mm3. The variation of signal amplitude was less than 20% among all pixels. The average energy resolutions of 11.7 ± 0.7 % and 13.7 ± 1.1 % were obtained for 662 keV gamma-rays, measured with 8x8 and 16x16 arrays, respectively. An attainable spatial resolution is < 0.8mm (FWHM) for 16x16 array in a reconstructed image. These results suggest the APD-based PET module can be a promising device for future applications, especially for high resolution MRI- and TOF-PET.

本文言語English
ホスト出版物のタイトル2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
ページ3542-3545
ページ数4
DOI
出版ステータスPublished - 2009 12 1
イベント2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 - Orlando, FL, United States
継続期間: 2009 10 252009 10 31

出版物シリーズ

名前IEEE Nuclear Science Symposium Conference Record
ISSN(印刷版)1095-7863

Conference

Conference2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
国/地域United States
CityOrlando, FL
Period09/10/2509/10/31

ASJC Scopus subject areas

  • 放射線
  • 核物理学および高エネルギー物理学
  • 放射線学、核医学およびイメージング

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