A new vibration control design method applying TMD (Tuned Mass Damper) to large-span architectural structures is proposed in this paper. In general, large-span architectural structures have various vibration modes involving rather high-order modes and those natural frequencies are closely spaced. Then, in order to control those modes, a spatially distributed MTMDs (Multiple TMD) method is proposed in this paper. Firstly we explain details of the proposed method on the spatial arrangement of MTMDs and the set-up procedure of design parameters. Next we apply the proposed method to a single layer lattice shell and compared its control performance to the conventional single TMD method.