Wall shear stress distribution inside growing cerebral aneurysm

Tetsuya Tanoue*, S. Tateshima, J. P. Villablanca, F. Viñuela, K. Tanishita

*この研究の対応する著者

研究成果: Article査読

38 被引用数 (Scopus)

抄録

BACKGROUND AND PURPOSE: Hemodynamic stimulation has been suggested to affect the growth of cerebral aneurysms. The present study examined the effects of intra-aneurysmal hemodynamics on aneurysm growth. MATERIALS AND METHODS: Velocity profiles were measured for 2 cases of AcomA aneurysms. Realistically shaped models of these aneurysms were constructed, based on CT angiograms. Flow fields and WSS in the models were measured by using particle image velocimetry and LDV. In 1 case, hemodynamic changes were observed in 4 stages of growth over a 27-month period, whereas no development was observed in the other case. RESULTS: The growing model had a smaller and more stagnant recirculation area than that in the nongrowth model. The WSS was markedly reduced in the enlarging region in the growing models, whereas extremely low WSS was not found in the nongrowth model. In addition, a higher WSSG was consistently observed adjacent to the enlarging region during aneurysm growth. CONCLUSIONS: The results indicated that the flow structure of recirculation itself does not necessarily lead to high likelihood of cerebral aneurysm. However, WSSG and WSS were distinctly different between the 2 cases. Higher WSSG was found surrounding the growing region, and extremely low WSS was found at the growing region of the growing cerebral aneurysm.

本文言語English
ページ(範囲)1732-1737
ページ数6
ジャーナルAmerican Journal of Neuroradiology
32
9
DOI
出版ステータスPublished - 2011 10
外部発表はい

ASJC Scopus subject areas

  • 臨床神経学
  • 放射線学、核医学およびイメージング

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