Which Is the best indicator of muscle oxygen extraction during exercise using NIRS? Evidence that HHb is not the candidate

Ryotaro Kime, Masako Fujioka, Takuya Osawa, Shun Takagi, Masatsugu Niwayama, Yasuhisa Kaneko, Takuya Osada, Norio Murase, Toshihito Katsumura

研究成果: Conference contribution

抄録

Recently, deoxygenated hemoglobin (HHb) has been used as one of the most popular indicators of muscle O2 extraction during exercise in the field of exercise physiology. However, HHb may not sufficiently represent muscle O2 extraction, as total hemoglobin (tHb) is not stable during exercise. The purpose of this study was to measure various muscle oxygenation signals during cycle exercise and clarify which is the best indicator of muscle O2 extraction during exercise using NIRS. Ten healthy men performed 6-min cycle exercise at both moderate and heavy work rates. Oxygenated hemoglobin (O2-Hb), HHb, tHb, and muscle tissue oxygen saturation (SmO2) were measured with near-infrared spatial resolved spectroscopy from the vastus lateralis muscle. Skin blood flow (sBF) was also monitored at a site close to the NIRS probe. During moderate exercise, tHb, O2-Hb, and SmO2 displayed progressive increases until the end of exercise. In contrast, HHb remained stable during moderate work rate. sBF remained stable during moderate exercise but showed a progressive decrease at heavy work rate. These results provide evidence that HHb may not sufficiently represent muscle O2 extraction since tHb is not stable during exercise and HHb is insensitive to exercise-induced hyperaemia.

本文言語English
ホスト出版物のタイトルAdvances in Experimental Medicine and Biology
ページ163-169
ページ数7
789
DOI
出版ステータスPublished - 2013
外部発表はい

出版物シリーズ

名前Advances in Experimental Medicine and Biology
789
ISSN(印刷版)00652598

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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