yes-Related protooncogene, syn, belongs to the protein-tyrosine kinase family

K. Semba, M. Nishizawa, N. Miyajima, M. C. Yoshida, J. Sukegawa, Y. Yamanashi, M. Sasaki, T. Yamamoto, K. Toyoshima

研究成果: Article査読

132 被引用数 (Scopus)

抄録

An src/yes-related novel gene named syn (SYN in human gene nomenclature) has been identified in the human genome on chromosome 6 and characterized by molecular cloning. Nucleotide sequence analysis of cDNA clones showed that the c-syn gene could encode a protein-tyrosine kinase that is very similar in primary structure to the v-yes and human c-src proteins. A 2.8-kilobase transcript of the c-syn gene, which differs in size from those of the c-yes, c-src, and c-fgr genes, was observed in various cell types. These results show that syn is a new member of the tyrosine kinase oncogene family.

本文言語English
ページ(範囲)5459-5463
ページ数5
ジャーナルProceedings of the National Academy of Sciences of the United States of America
83
15
DOI
出版ステータスPublished - 1986
外部発表はい

ASJC Scopus subject areas

  • General

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