Ytterbium-catalyzed synthesis of dihydropyridines

Shunsuke Sueki, Ryo Takei, Junya Abe, Isao Shimizu

研究成果: Article査読

16 被引用数 (Scopus)

抄録

The reaction of anilines, benzaldehydes, and ethyl 3,3-diethoxypropionate in the presence of Yb(OTf)3 proceeded under mild reaction conditions to give dihydropyridines (DHPs). We have found that the reaction depended on the solvent and the DHPs were obtained selectively in 1,4-dioxane as a solvent. Various 2,6-unsubstituted DHPs were synthesized in one pot in satisfactory yields.

本文言語English
ページ(範囲)4473-4477
ページ数5
ジャーナルTetrahedron Letters
52
34
DOI
出版ステータスPublished - 2011 8 24

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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